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Curological Review - A Personalized Acne Treatment Subscription?

Summary of the curology review

Curology offers personalized acne treatment plans that do not require doctor appointments. Find out more in our Curology Review!

Ankeeta Shah


Curology creates bespoke skin treatments for patients that are completely online, although they may be more expensive than alternative skin products.

7 facts from our Curology Review

  1. Location: San Diego, CA.
  2. Products: Custom Prescription Skin Care "Superbottle"
  3. How it works: A dermatologist will review the patient's information and provide a custom acne treatment formula
  4. Privacy: Passing on of aggregated customer data to third parties
  5. Costs: small bottle monthly ($ 19.95 + $ 4.95), large bottle every two months ($ 39.90 + free shipping and handling), large bottle of detergent and moisturizer every two months ($ 59.90 + free shipping and Processing)
  6. reviews : Good Excellent
  7. Complementary products :: Nebula Genomics (DNA test that decodes 100% of DNA and provides reports on skin conditions)

Curology introduction

This is an overview of Curology, a prescription skin care startup that was founded in 2014 by Dr. David Lortscher was founded. Dr. Lortscher wants to debunk the idea that skin care is one size fits all. In fact, Curology creates bespoke treatments for those with acne who otherwise would not have easy access to dermatologists. These treatments are delivered directly to the patient - no personal visit to a doctor is required. To date, the company has cared for patients in over 35 countries.

A primer for skin and acne

Before we dive into curology, let's summarize some facts about skin health and acne.

Why is skin health important?

The skin is the largest organ in your body. It acts as a protective barrier between you and everything else in the outside environment. The skin is mainly made up of cells known as keratinocytes. These cells are essential - they perform three main functions. First, they prevent foreign substances from entering the body. Second, they also minimize the loss of moisture and heat from the body. Ultimately, these cells are necessary to maintain the structural integrity of the skin structure by forming close bonds with one another and with other cells that make up the skin.

The skin is divided into three layers: the hypodermis, dermis, and epidermis. Keratinocytes are the most common cell type in the epidermis, the outermost layer. The epidermis contains hair, hair follicles, and sebum glands. The sebum glands secrete sebum, an oily, waxy substance produced by fat cells. Sebum naturally moisturizes the skin and prevents it from becoming dry and irritated. However, excessive sebum production can lead to acne.

What is acne

Acne vulgaris, better known as acne, is an inflammatory skin disease that causes hair follicles to become clogged with sebum, dead skin cells, and bacteria. Acne is incredibly common - it affects 50 million people in the United States. There are a number of different types of acne that can appear on the face and body, including closed clogged follicles (whiteheads), open clogged follicles (blackheads), pimples (pustules), etc. Acne is difficult to treat because it depends on several factors can be attributed. Acne can be caused by factors that can be controlled, including environmental factors (e.g. hormonal changes, diet, stress) and factors that cannot be controlled, such as genetic predispositions to acne.

Review of curology

30 Day Free Trial ($ 4.95) Review

You don't have to make a personal appointment with a dermatologist. The curology department offers convenient access to dermatological care from your phone. Customers use their Curology login to upload photos of their face and neck. You will also fill out a questionnaire highlighting how often you get acne, what acne treatments have been used in the past, what medications you are currently taking, and what skin care goals are for.

The photos and questionnaires are sent to a board certified dermatologist (e.g., dermatologist or assistant to a dermatologist) through the brand's website. This provider evaluates the client's skin profile, skin type, and medical history, and then creates a custom treatment plan. Treatment includes a custom formula also known as a "superbottle". This is a compound prescription cream that contains three clinically proven active ingredients that can help clear acne and provide additional whitening and antiaging benefits (such as reducing clogged pores). dark spots and fine lines). The active ingredients of curology can include:

  • Azelaic acid: Skin peeling (i.e. peeling off dead skin). It also disrupts the enzyme that catalyzes melanin (tyrosinase), effectively reducing hyperpigmentation.
  • Clindamycin: An antibiotic that can fight acne-causing bacteria.
  • Metronidazole: An antibiotic that can fight rosacea.
  • Niacinamide: Vitamin B3 antioxidant that protects the skin from environmental damage and reduces inflammation.
  • Tranexamic acid: A synthetic derivative of the amino acid lysine. Combats hyperpigmentation.
  • Tretinoin: Increases cell turnover.
  • Zinc pyrithione: An antibacterial and antifungal agent that restores balance to the skin and prevents unwanted bacteria from growing on your skin.

Many of these ingredients work against both acne and aging.

Most customers start with a 30 day free trial of Curology, where individuals can get a custom super bottle for free for a month with only $ 4.95 for shipping and handling. The dispatch takes place within 1 to 3 days. In addition to a custom super bottle, customers receive two other items - a pH balanced cleaner and a curology moisturizer. In addition, customers have access to the above-mentioned provider who is available for questions and suggestions, e.g. B. Various over-the-counter cleansing and moisturizing creams, dietary recommendations, etc. The insurance does not cover curology.

Review of curology costs and subscription plans

After a 30-day trial period, patients can still receive monthly or bimonthly super bottles.

What does curology cost?

  • Small bottle (14 ml) super bottle: $ 19.95 + $ 4.95 shipping (every 30 days)
  • Large bottle (27 ml) super bottle: $ 39.90 with free shipping (every 60 days)
  • Large bottle (27 ml) superbottle with detergent and moisturizer: $ 59.90 with free shipping (every 60 days)

To cancel the curology: To cancel, customers can click the “I want to cancel” button at the bottom of the payment page. This starts the cancellation process.

Verification of curology privacy

While privacy is important to curology, it's not necessarily the company's focus. The company collects and stores a wide variety of personal and health information from customers. Personal information includes name, date of birth, gender or gender, address, order history, etc. Health information includes medical history, medication, allergies, photos for diagnosis purposes, etc. This information is primarily used to provide online dermatology services so that this information passed on to licensed providers. However, Curology can also pass on non-personal, unidentified, aggregated customer data to third-party providers. Ultimately, the company retains customer information, especially medical records, for five years.

Further information can be found under Curology Data Protection Regulations.

Other curological reviews

Does the curology work? Customer reviews are mixed. Some patients saw results and some did not.

Advantages and disadvantages of curology

The genetic basis of acne

Aside from consulting dermatologists and building effective skin care routines, there are certain aspects of acne that you cannot control, such as: B. Your genetics. Let's end our curology review with a look at acne genetics.

Acne Twin Studies

Acne is strongly genetic. If you have a parent or sibling with acne, you are four times more likely to develop acne as well.

Based on a study of ~ 1,500 identical and fraternal twins, it is estimated that the heritability of acne is 81%. Other acne studies have looked at whether there is a link between genetics and sebum production, which is one of the factors involved in acne occurrence. A study on a small sample of 20 pairs of identical and fraternal twins found that sebum production is genetically controlled, but the resulting severity of acne varies and is likely determined by a combination of genetic and environmental factors.

Overall, this highlights the difficulty and complexity in understanding the etiology of acne.

Acne genome-wide association studies

More systematic evidence of the genetic basis of acne was elucidated by genome-wide association studies (GWAS).

When examining the genomes of ~ 7,000 individuals in the UK, a group of researchers identified three genomic loci associated with the disease. The identified loci also provided insight into the putative biological mechanisms underlying the genetic basis of acne. For example, these loci are linked to the OVOL1 , FST , and TGFβ2 Genes that are all involved in transforming growth factor beta (TGFβ ) Signal path. The TGFβ pathway is involved in a number of different processes including cell growth, programmed cell death, also known as apoptosis.

A recent study examining the genomes of ~ 27,000 individuals identified a total of 15 acne-associated loci, 12 of which are new. Some of the novel loci are linked to the WNT10A and SEMA4B Genes. Overall, these loci explain only 22% of acne heritability, underscoring the fact that more studies need to be done.

Once we have a more complete understanding of the genetic makeup of acne, we can develop more effective treatment options for patients.

Nebula Genomics

At Nebula Genomics, our goal is to enable you to learn more about your genome, including your genetic predispositions to skin conditions such as acne. This can help you determine the best skin care regimen for you before buying products like Curology.

If you've already participated in 23andMe or AncestryDNA, you can upload your DNA data for free and receive an extended DNA report. We use a process called imputation to fill in the gaps that typical DNA testing has left. As a customer, you will have access to hundreds of features and curated research studies via the internet, Nebula Research Library keeping you up to date with the latest research, including research on skin health and what it means to you and your DNA.

In addition, we offer the cheapest 30x whole genome sequencing service! This genetic test reads 100% of your DNA. That's 10,000 times more data than tests like 23andMe or AncestryDNA!


Let's summarize our curology overview.

Curology is one of many telemedicine based companies focused on treating acne. Its main advantage is that it is possibly the most customized acne treatment option there is, especially when compared to alternatives like Proactiv and yours. This is because consulting a licensed provider is included in the fee.

Ultimately, curology is an affordable and accessible alternative to expensive personal dermatology visits, which can cost up to $ 1,000 per year.

Are you interested in other acne treatments? Check out Arbonne, Yours, Proactiv, CleaRx, and Plexaderm.

And you might be interested in these companies that are good at supporting aging:

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  • TeloYears (uses telomere length to assess biological age)
  • Test Boost max (testosterone booster)
  • Tru Niagen (supplement to slow down aging)
  • Vegamour (herbal hair care products)
  • Viviscal (hair growth and thickening supplement)

Plus, Pathway Genomics offers a clinical DNA test specifically for skin information!

Did you like our Curology Review? You can read more reviews on our blog and check out our Complete Guide to the Best DNA Testing Kit and Other Home Tests.