What is the definition of cellular organization

Cellular biotechnology

The work of the Cellular Biotechnology Department focuses on the extracorporeal use and processing of adherent growing cells. These cells can be of human origin, but are also isolated from other mammals for special purposes. By establishing the German Cell Bank for Wild Animals, the EMB can access many different species for cellular applications.

In addition to cell-based therapeutic approaches, the department also develops new cellular test and model systems. For this purpose, not only cellular but also organotypical systems are built up. These are either isolated directly from the organism and cryopreserved until they are used, or they are reconstructed from the isolated cells by organoid formation.

In addition to differentiated primary isolations, stem cells from exocrine glands, especially sweat glands, are used as the cell source. The EMB holds several patents for these cell types as well as for the reconstructed cell aggregates.

The test systems for the pharmaceutical and cosmetics industries focus primarily on the properties of the skin, such as perspiration and wound healing, as well as the influence of various substances on nerve cell function. In the therapeutic area, the use of sweat gland cells for wound healing is being tested. All preclinical studies carried out to date show a clear improvement in wound healing through the use of stem cells derived from sweat glands. In the next step, these cells will be used in the clinic.